BioGems Ionomycin Calcium Salt

Catalog Number : 5608212
descriptionIonomycin is an ionphore discovered in Streptomyces conglobatus and used in the study of intracellular calcium.

It is also reported to stimulate the intracellular production of IL-2, IL-4 and perforin. It is supplied as a a calcium salt for ease of storage.

Molecular Formula:
C41H70O9 Ca

Molecular Weight:
747.1
CAS Number
56092-82-1
Purity:
≥98%
Storage Conditions:
Product should be kept at -20°C.
References:
Liu, C. M., & Hermann, T. E. (1978). Characterization of ionomycin as a calcium ionophore. Journal of Biological Chemistry, 253(17), 5892-5894.

Morgan, A. J., & Jacob, R. (1994). Ionomycin enhances Ca2+ influx by stimulating store-regulated cation entry and not by a direct action at the plasma membrane. Biochem. J, 300, 665-672.

Elzi, D. J., Bjornsen, A. J., MacKenzie, T., Wyman, T. H., & Silliman, C. C. (2001). Ionomycin causes activation of p38 and p42/44 mitogen-activated protein kinases in human neutrophils. American Journal of Physiology-Cell Physiology, 281(1), C350-C360.