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- 详细信息
- 技术资料
- 免疫原:
peptide
- 亚型:
IgG1
- 形态:
Liquid
- 保存条件:
-20℃
- 克隆性:
mAb
- 适应物种:
Human
- 保质期:
1年
- 目录编号:
TD-31935
- 级别:
科研级
- 库存:
88
- 供应商:
武汉天德
- 宿主:
Mouse
- 应用范围:
FCM、ELISA、IHC、WB、ICC
- 靶点:
详询
- 抗体英文名:
Mouse Monoclonal Antibody to CD45R
- 抗体名:
CD45R
- 规格:
100ul/50ul
| 规格: | 100ul | 产品价格: | ¥2180.0 |
|---|---|---|---|
| 规格: | 50ul | 产品价格: | ¥1280.0 |
Mouse Monoclonal Antibody to CD45R
Description |
|
| The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. | |
Specification |
|
| Aliases | PTPRC; LCA; LY5; B220; L-CA; T200; CD45; GP180 |
| Entrez GeneID | 5788 |
| Swissprot | P08575 |
| clone | 2H3E2 |
| WB Predicted band size | 147.5kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Purified recombinant fragment of human CD45R (AA: extra 378-577) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
| WB | 1/500 - 1/2000 |
| IHC | 1/200-1/1000 |
| ICC | 1/200 - 1/1000 |
| FCM | 1/200-1/400 |
| ELISA | 1/10000 |
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CD45R
¥1280 - 2180









