Factor H/CFH蛋白 | Human Factor

| 产品信息

品名:NebuSelect™ Recombinant Human Factor H/CFH, His-tag

货号:NBL-242814

品牌:Nebulabio

规格:100ug；1mg；Bulk

| 产品描述

NebuSelect™ Recombinant Human Factor H/CFH, His-tag(Cat#NBL-242814) is expressed in HEK293 with His tag at the C-Terminus.It contains Ser860-Arg1231.

| 产品属性

表达系统:HEK293

标签:His-tag

靶点名称:Factor H/CFH

物种：Human

分子量：The protein has a predicted MW of 42.8 kDa. Due to glycosylation, the protein migrates to 60-68 kDa based on Bis-Tris PAGE result.

氨基酸序列：

Accession: P08603-1

纯度:＞95%

内毒素：＜1EU/ug(LAL Method)

储存运输条件: Short term 4℃; Long term -20℃.

| 靶点信息

Factor H is the major soluble inhibitor of complement, where its binding to self markers (i.e., particular glycan structures) prevents complement activation and amplification on host surfaces. Not surprisingly, mutations and polymorphisms that affect recognition of self by factor H are associated with diseases of complement dysregulation, such as age-related macular degeneration and atypical haemolytic uremic syndrome. In addition, pathogens (i.e., non-self) and cancer cells (i.e., altered-self) can hijack factor H to evade the immune response.

For Research Use Only!

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